COST ACTION 920

Inventory of QMRA Studies in Europe


Data sheet

Pathogen

Salmonella Enteritidis

Country or region

The Netherlands

Transmission route

 From

ingestion

To

infection

Specific product(s)

experimental studies in rats

End-point(s)

systemic infection


Reports or publications

Bibliographic reference

Havelaar AH, Garssen J, Takumi K, Koedam MA, Dufrenne JB, Van Leusden FM, De la Fonteyne LM, Bousema JT, Vos JG. A rat model for dose-response relationships of Salmonella Enteritidis infection. J Appl Microbiol 2001;91:442-452.

Takumi K, Garssen J, Havelaar A. A quantitative model for neutrophil response and delayed-type hypersensitivity reaction in rats orally inoculated with various doses of Salmonella Enteritidis. Int Immunol 2002;14:111-119.

Havelaar A, Garssen J, Takumi K, Koedam M, Ritmeester W, De la Fonteyne L, Bousema T, Vos J. Intrapsecies variability in the dose response relationship for Salmonella Enteritidis, associated with genetic differences in cellular immune response. J Food Prot 2004;67:2008-1015.

Abstract

This is a series of papers using experimental infection in rats to study dose-response relationships and within-host dynamics of infection.

Status

On-going

Availability

published papers


Project group

Institute

RIVM, P.O. Box 1, 3720 Bilthoven, the Netherlands

Contact person

Arie.Havelaar@rivm.nl

Partners